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The Department of Pharmacology opened its door together with the University of Pharmacy (Yangon) in January, 1992. The first chair of this Department was Prof. Dr. Mya Mya Than and the current head of Department is Professor Dr. Ei Ei Mon.
In the undergraduate teaching curriculum, Pharmacology had been put as one of the major subjects for students from second year to fourth year since the beginning. From 2003 to 2017, Pharmacology had been taught as one of the major subjects in general training of Master of Pharmacy (M.Pharm.). The Department initiated Ph.D program in Clinical Pharmacy since January, 2014, and Master program in Clinical Pharmacy since January, 2018.